This page provides a simple power estimator for drug-outcome research. For each drug ingredient and each Health Outcome of Interest, an estimated minimal detectable relative risk (MDRR) can be computed. This MDRR can be detected given the population size of the database and the frequency of drug and outcome in 10 age and 2 gender strata:
The MDRR decreases over time with more and more drug exposure. It is important for newly introduced drugs to know when sufficient sample size has accumulated to power a MDRR of as low as necessary to detect typical drug outcome risks. This following provides the MDRR over time for detection the 35 HOIs for all drugs introduced to the market between 2003 and 2009 .